Isonicotinic Acid Hydrazide
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منابع مشابه
Synthesis and structural studies of complexes of Cu, Co, Ni and Zn with isonicotinic acid hydrazide and isonicotinic acid (1-naphthylmethylene)hydrazide
Eight new complexes of Cu(II), Co(II), Ni(II) and Zn(II) with isonicotinic acid hydrazide (isoniazid, (INH)) and isonicotinic acid (1-naphthylmethylene)hydrazide (INNMH), having the formula of the type [M(INH)(ac)2] or [M(INNMH)(ac)2] (M = Co(II), Ni(II) and Zn(II)) and [Cu(INH)(ac)2]2, [Cu(INNMH)(ac)2]2, were synthesized and characterized. All complexes were characterized based on elemental an...
متن کاملCharge Transfer Interactions between Isonicotinic Acid Hydrazide and Cupric Ions
The interaction of Cu2+ with isonicotinic acid hydrazide (INH) and some of its derivatives has been investigated by means of electron spin resonance, nuclear magnetic resonance, and optical absorption studies. It could be shown that an interaction exists between the metal ions and the hydrazine side chain in addition to the very weak interaction with the ring nitrogen. The results obtained indi...
متن کاملRadical scavenging activities of niacin-related compounds.
We investigated whether niacin-related compounds had radical-scavenging activity by electron spin resonance methods. Many compounds, but not trigonelline, had radical-scavenging activity against hydroxyl radicals. However, for the nitric oxide radical and 1,1-diphenyl-2-picrylhydrazyl radical, only nicotinic acid hydrazide and isonicotinic acid hydrazide had scavenging activities. These results...
متن کاملPeroxidase-mediated oxidation of isoniazid.
Oxidation of isonicotinic acid hydrazide (isoniazid) by horseradish peroxidase at the expense of H2O2 yielded reactive species which were able to reduce nitroblue tetrazolium and bleach p-nitrosodimethylaniline. Nicotinic acid hydrazide oxidation did not cause these effects. At slightly alkaline pH, oxidation of isonicotinic acid hydrazide by horseradish peroxidase proceeded at the expense of m...
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